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10.1038/nrclinonc.2016.25 38 KongZ.LiuR.ChengY

Frontiers in Pharmacology, 13, Article 1026182

In 1956, 500 mg tablets went on sale in the United Kingdom under the trade name Panadol, advertised as being gentle to the stomach since other analgesics of the time contained aspirin, a known stomach irritant