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Firstly, most of research on the anti-hair greying effects of natural products and their derivatives are preclinical experiments

Iron overload enhances oxidative stress and the NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome signaling, triggering the evolution of several inflammatory mediators, resulting in a cascade of inflammatory responses and renal dysfunction in iron-overloaded rats (Chaudhary et al., 2018)

Porous and nanofiber A-chitosan obtained from blue crab (Callinectes sapidus) tested for antimicrobial and antioxidant activities

In addition, the mice also showed the phenotypes of increased mitochondrial oxidative stress, histopathological changes, and abnormal mitochondrial ultrastructure in cardiomyocytes