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Individuals in the exposed group have been residents in the gold mining districts for at least the last 5 years prior to the study and had direct contact with Hg vapors in the last year

Administration technique Subcutaneous injection using insulin syringes represents the standard administration method for both peptides

EDC-receptor complexes are able to mediate genomic actions by binding to hormone response elements to activate or repress downstream gene transcription

Ethics declarations Ethics approval and consent to participate This study was performed in strict accordance with the NIH guidelines for the care and use of laboratory animals and approved by the Institutional Ethics Committee of the Faculty of Biochemistry and Biological Sciences (UNL, Santa Fe, Argentine - Acta CE2022-63)