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Description

ALAS exists in two isoforms: ALAS1 (ubiquitous) is feedback-inhibited transcriptionally by heme and induced by drugs metabolized by heme-containing cytochrome P450 enzymes

Its an evidence-based complement to microneedling, phototherapy, or topical skin care regimens

However, the limitation of this research lies in the lack of in vivo studies with animal models, leading to insufficient validation of its in vivo efficacy and mechanisms

Reversible Toxic Effects of the Dietary Supplement Indole-3-Carbinol in an Immune Compromised Rodent Model: Intestine as the Main Target, J Diet Supplements, vol