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Category 2 removal can be a procedural step, but 503A compounding legality depends on the bulks list process and FDA actions (including rulemaking), plus compliance with sourcing requirements (FDA Law Blog)

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Thymosin Alpha-1, for example, has a plasma half-life of approximately 2 hours but exerts immunomodulatory effects for considerably longer periods, likely because of downstream signaling cascades that persist well beyond peptide clearance