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Although the precise mechanism underlying modulation of autophagy remains elusive, the current understanding leans towards the notion that upregulation of autophagy confers a protective effect on tumor cells

The methods to overcome drug resistance according to the autophagy mechanism are mainly limited in the current research to the inhibition of autophagy by autophagy inhibitors

SIRT3 plays a bifunctional role in cancer, either tumor-promoting or tumor-suppressing, depending on the cancer type and the status of intracellular signaling pathways (Xiong et al

Neuro20 bypasses those barriers, forcing adaptation at the cellular level