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200 Enzyme-catalyzed reactions that generate ROS include those involving NADPH oxidase, xanthine oxidase, uncoupled endothelial nitric oxide synthase (eNOS), arachidonic acid and metabolic enzymes such as the cytochrome P450 enzymes, lipoxygenase and cyclooxygenase

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Melanin-like nanoparticles as an alternative to natural melanin in retinal pigment epithelium cells and their therapeutic effects against age-related macular degeneration