foxo4 dri senolytic peptide human trial 2024 2025 Targeting Senescence: A Review of Senolytics and Senomorphics in Anti-Aging Interventions CHK2-USP37 axis stabilizes FOXO4 to

CHK2 USP37 axis stabilizes FOXO4 to sustain senescence and evade apoptosis PNAS Senescent cells as a target for anti aging interventions: From senolytics to immune therapies PMC FOXO4 DRI improves spermatogenesis in aged mice through reducing senescence associated secretory phenotype secretion from Leydig cells ScienceDirect FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology

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