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Speaking about the study, co-author Steven Silverstein said, Cigarette smoke consists of numerous compounds that are harmful to health, and it has been linked to a reduction in the thickness of layers in the brain, and to brain lesions, involving areas such as the frontal lobe, which plays a role in voluntary movement and control of thinking, and a decrease in activity in the area of the brain that processes vision. He further added that previous studies have pointed to long-term smoking as doubling the risk for age-related macular degeneration and as a factor causing lens yellowing and inflammation