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A comprehensive analysis and anti-cancer activities of quercetin in ROS-mediated cancer and cancer stem cells

In the H 2 S metabolic regulatory network, sulfide:quinone oxidoreductase (SQOR) is a crucial rate-limiting enzyme ( 2 S to chemically more stable persulfides, the first and irreversible step of the sulfide oxidation pathway

(2020) reported that irisin activates the Nrf2 pathway, which is known to regulate proteasomal function and oxidative stress responses, potentially contributing to reduced protein aggregation 33