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To determine if GABA reduction in the sensorimotor cortex is associated with dysfunction of supraspinal GABAergic neurons, we performed transcranial magnetic stimulation studies to assess intracortical inhibition and excitation [20]

Abstract Background Glutathione s-transferases (GSTs) perform an essential role in detoxification of xenobiotics and endogenous compounds via their conjugation to reduce glutathione

These studies suggest that the safe use of Tylenol during pregnancy does not appear to increase the risk of autism in children

Collectively, these sex-divergent transcriptional programs support an endocannabinoidglucocorticoid (eCB-GC) cross-talk model in which prenatal stress elevates glucocorticoid tone while THC disrupts CB-mediated feedback, jointly altering metabolic homeostasis, glial development, and synaptic refinement during adolescent corticolimbic maturation