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Watch an In-Depth Video on Everything You Need to Know About Vitamin B12 Length: 51 minutes References (3) Chawla J1, Kvarnberg D2

Nonetheless, household exposure is probably more relevant than public exposure, and the continued declines in smoking rates as well as health regulations outlawing smoking in indoor public spaces will further mitigate the effects of SHS

Intramuscular replacement therapy is indicated for patients with: Significant B12 deficiency (thresholds depend on local laboratory reference ranges) Neurological symptoms or signs Pernicious anaemia Malabsorption syndromes The standard UK regimen for patients without neurological involvement involves hydroxocobalamin 1mg intramuscularly three times weekly for two weeks, followed by maintenance injections every 2-3 months (often 3-monthly)