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Following the loss of dopamine-producing neurons, there is a subsequent degeneration of other neuronal subtypes, giving rise to symptoms unresponsive to dopamine modulation

[DOI] [PMC free article] [PubMed] [Google Scholar] 71.Seah A., Aik J., Ng L.-C., Tam C.C

[1] The forward pathway is present in several bacteria, such as Escherichia coli [2] and Bacillus subtilis , [3] and involves the transfer of the thiol group from cysteine to homocysteine (methionine precursor with the S-methyl group), thanks to the -replacement of the acetyl or succinyl group of a homoserine with cysteine via its thiol group to form cystathionine (catalysed by cystathionine -synthase, which is encoded by metB in E

PloS One (2011) 6(4):e18604