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Phillips CL, Yang Q, Williams A, Roth M, Yee BJ, Hedner JA, et al

van Beers JJ, Schwarte CM, Stammen-Vogelzangs J, Oosterink E, Bozic B, Pruijn GJ

Beyond the breakdown While breaking down immunogenic gluten-derived peptides is a promising and thoroughly explored strategy for treating celiac disease, researchers are also developing therapeutics to block the immune response to gluten downstream

62 UPS-targeted therapies and induced protein degradation strategies Recent advances in targeted protein degradation have transformed the ubiquitinproteasome system into a highly versatile therapeutic platform