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The nozzle of the spray bottle should always be kept sterilized and sanitary at all times to prevent any degradation or bacterial contamination of the product

Other potential triggers include (2,3): Foods (especially nuts, eggs, shellfish, dairy, strawberries, and food dyes) Medications Insect bites or stings Temperature shifts (heat, cold, sweating) Pressure or friction on the skin Environmental allergens (pollen, pet dander, etc.) Bacterial infections Many times, the cause is never definitively identified, especially when hives occur in the setting of a viral infection

doi: 10.1016/0014-4800(90)90070-T

(2) Calming Inflammation GHK-Cu lower pro-inflammatory signals, which are key drivers of inflammation in older skin