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For the group of hypothyroid patients with precipitating causes, like autoimmune disease, immunosuppressive treatment, or handling of the autoimmune response might also be implemented along with thyroid hormone replacement (Men et al

[32] Alongside GABAergic mechanisms, GABA has also been detected in other peripheral tissues including intestines, stomach, fallopian tubes, uterus, ovaries, testicles, kidneys, urinary bladder, the lungs and liver, albeit at much lower levels than in neurons or -cells

The latter then can be degraded by catalase (CAT), ascorbate peroxidase (APX) and several other enzymes (Figure 1)