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Furthermore, sesamin-treated mice maintained higher levels of endogenous antioxidants for example, superoxide dismutase (SOD) activity was increased relative to untreated MPTP mice, and striatal TH levels were better preserved, indicating reduced dopaminergic neuron damage (66)

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The pathway leads to the generation of several sulfur metabolites, which include cysteine, GSH and the gaseous signalling molecule hydrogen sulfide (H 2 S)

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Gene therapy directly addresses the genetic cause of HCU, offering the possibility of durable metabolic correction

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Immediately prior to infection, the temperature setpoint was either maintained at 37C or changed to a range of temperatures between 31C and 38.5C across multiple experiments with each condition performed in duplicate (Table 1

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