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The levels of H3K27me2, H3K27me3, H3K9me2, and DNA methylation on the RORA promoter were, however, not significantly different, pointing to the efficacy of the co-analysis of specific epigenetic markers with the gene expression of key neural developmental genes as predictors of ASD occurrence from as young as newborn babies [182]

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the single controlled insomnia trial most often cited showed modest effects at best