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Biochem J 1977;64:469-72

There is just one snag

FIGURE 2 Elimination of Branch and By-Product Metabolic Pathways To reduce L-aspartate--semialdehyde shunting via branch metabolism, the genes lysA (encoding diaminopimelate decarboxylase) and thrA (encoding aspartate kinase/homoserine dehydrogenase) in E