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Of note, RNA-seq analysis of XKR8-deficient neutrophils revealed minimal changes in global gene expression, indicating that loss of XKR8 does not significantly alter the transcriptional profile of neutrophils (Extended Data Fig

doi: 10.3389/fnins.2026.1819436 Received 27 February 2026 Revised 29 March 2026 Accepted 30 March 2026 Published 13 April 2026 Volume 20 - 2026 Edited by Magdalena Sowa-Kuma, University of Rzeszow, Poland Reviewed by Wuyang Wang, Xuzhou Medical University, China Guangheng Zhang, Chengdu University of Traditional Chinese Medicine, China Updates Copyright 2026 Yao, Yan and Sun

Having shown this calculus, the RMSE of our predictions of SOCd is 0.5 on the logarithmic scale, which refers to point predictions