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Results Elevated dependence on extracellular glutamine and cystine in TNBC cells To investigate the dependence of breast cancer (BC) cells on glutamine (Gln), we first assessed cell proliferation under Gln deprivation and the sensitivity to the glutaminase (GLS1) inhibitor CB839 in luminal BC cell lines (CAMA-1, ZR-75-1, T47D, and MCF7) and TNBC cell lines (MDA-MB-231, SUM159, Hs578T, and its invasive subclone Hs578Ts(i) 8 ) after 72 h of culture (Fig

NPY is still in relatively early stages of clinical translation for psychiatric applications