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Description

GPx is a tetrameric enzyme with seleno-cysteine (SeC) as a cofactor in its active site

As a mitochondrial enzyme, HOT can strongly influence D -2HG availability by coupling iron metabolism with MYC gene activation, thereby indirectly affecting IDH2 activity (48)

High plasma glial fibrillary acidic protein levels are associated with an increased risk of dementia and Alzheimers disease over a 13year followup period: results from a prospective populationbased cohort