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This observation collectively suggested that cPLT carriers reduced the uptake of NPs by the reticuloendothelial system and promoted efficient accumulation within the plaque

These typically manifest as mild redness, swelling, or tenderness lasting 24-48 hours post-injection

6 This lactylated HMGB1 is released from macrophages via exosome secretion, which increases endothelium permeability, thereby exacerbating polymicrobial sepsis progression