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In the CY 2023 PFS proposed rule, commenters noted for ACOs participating in the Shared Savings Program reporting all payer/all patient eCQMs/MIPS CQMs there are issues related to meeting all-payer data requirements, data completeness requirements, and data aggregation (87 FR 69837)

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Hambright WS, Fonseca RS, Chen L, Na R, Ran Q (2017) Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration