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One aspect of the invention pertains to treating an NNMT-expressing cancer, such as glioblastoma, by administering a therapeutically effective amount of one or more cations of the invention with concurrent administration of one or more cations chosen from Tables 3a and 3b

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Another question for future studies is which organ-specific aging proteins are causal drivers of aging, given that multiple plasma proteins have been shown to directly modulate aging phenotypes 8