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However, the intrastriatal approach is an acute, high-dose exposure that bypasses normal physiological regulation and therefore does not accurately model environmental overexposure

Papaverine is currently not licensed for treatment of ED

10.3389/fcimb.2023.1196084 87 ShiX.ZhangJ.MoL.ShiJ.QinM.HuangX

The secondary endpoint included changes in glucose, insulin, HOMA-IR, blood pressure, lipid profiles, uric acid, free fatty acids, hepatic profile, and the sensation of fatigue and hunger