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Proc Natl Acad Sci U S A 107:1556570

There was also a cardioprotective effect of spermidine as demonstrated by Wang et al

A similar process takes place during lactation and during sexual activity

A separate 2025 PubMed-reviewed paper on BPC-157 in orthopaedic sports medicine noted that the peptide showed positive outcomes in 87.5% of reviewed knee pain cases though the paper called out heterogeneity in study design and dosing protocols