acetyl-l-carnitine and cancer treatment Clinical Significance of Carnitine in the of Cancer: From Traffic to the Regulation Acetyl-L-carnitine in chronic pain: A

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The underlying molecular mechanism involves the dysregulation of core clock genes, particularly the significant upregulation of the Per2 protein, which interacts with HIF1 and leads to the upregulation of key downstream cell cycle genes (e.g., Ccnb2, Cdc20, Espl1), ultimately promoting cell cycle progression and inhibiting apoptosis [204]

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doi: 10.1016/j.ejphar.2023.175719 314 MurrayANguyenTMParkerCEFeaganBGMacDonaldJK