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FIGURE 2 3.2.1 HIF-1 Renal hypoxia is a common feature across various AKI models, regardless of the initiating insult

Not all medications and nutrients are small enough to get absorbed or need breakdown via gastric enzymes for activation for the sublingual route, but whenever possible there is a benefit to using this route as it bypasses potential damage/absorption issues in the GI tract

It affects children from all backgrounds, cultures, and walks of life

Additionally, Minuk and Lewkonia (1986) have even reported familial clustering of Inflammatory Bowel Disease (IBD) and MS, suggesting that they have genetic or environmental risk factors in common