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The bioavailability of supplemental acetyl-L-carnitine has not been as well studied, though some evidence suggests slightly higher circulating concentrations compared to equivalent L-carnitine doses, with peak plasma levels typically achieved 24 hours after oral administration [5][12]

Furthermore, 9 weeks of LC supplementation in conjunction with resistance training revealed a significant increase of circulating total antioxidant capacity and glutathione peroxidase activity and decrease in malondialdehyde concentration [43]