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The difference between the two treatments is how they achieve this

People taking biologics have sometimes reported the following health problems, though these are rare: lymphoma certain blood disorders (bleeding, bruising) severe allergic reactions liver damage neurological problems, including numbness, weakness, tingling, or visual disturbances, such as blurred vision, double vision, or partial blindness Biologics offer an advantage in treating Crohns disease because these drugs specifically target the substances in your body that cause bowel inflammation

Severe or persistent diarrhea (could indicate C difficile infection)

The addition of epinephrine prolongs the anesthetic effect by constricting blood vessels, minimizing bleeding, and reducing the rate of systemic absorption