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doi: 10.1016/j.redox.2019.101107 57 SunXOuZChenRNiuXChenDKangRet al

b , Genomic PCRs of the 14 Pfa1 cell clones that remained clones after the removal of false-positive results using human-specific primers to amplify the human cDNAs of GPX4 (571 bp) or AIFM2 (524 bp)

In summary, this glycolysis-centered metabolic reprogramming not only provides essential energy for the abnormal proliferation of leiomyoma cells but also influences the physiological state of surrounding tissues by altering the metabolic microenvironment (such as acidification and lactate signaling), constituting a key mechanism for the sustained growth of uterine fibroids