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The exo-8, 9-epoxide metabolites of AFB1 are surprisingly prone to construct DNA adducts

Conserved actin cysteine residues are oxidative stress sensors that can regulate cell death in yeast

While serine and glycine starvation or PHGDH inhibition alone had no detectable effect on gut morphology, we did note a significant decrease in the length of intestinal villi in animals co-treated with the -SG diet and PH755 (Supplementary Figure 6f), consistent with the greater weight loss seen in these mice