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1 When diabetic patients are not at risk of DKA, basal insulin plus noninsulin hypoglycemic agents with weight loss effects are recommended for those with preobesity/obesity or without weight loss, and basal insulin/premix insulin plus secretagogues or DPP-4i are recommended for those without preobesity/obesity and with weight loss concerns

Furthermore, chronic exposure to excess iron leads to heme-mediated export of the tumor suppressor p53 out of the nucleus in both in vitro and in vivo models of pancreatic cancer, resulting in the promotion of EMT [79]

EXPIRATION DATE: 30 NOV 2027