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Given the limited therapeutic options for HD, Lim and colleagues investigated the neuroprotective properties of the ketone body D-BHB in R6/2 HD transgenic mice

10.1016/j.fufo.2022.100205 91 MafeA

For example, by upregulating the E3 ubiquitin ligase STUB1, which encourages GPX4 ubiquitination and associated destruction, sanguinarine affects ferroptosis [69]