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Vitamin C (L-Ascorbic Acid and derivatives): A potent antioxidant, Vitamin C is celebrated for its ability to brighten the complexion, reduce the appearance of dark spots and hyperpigmentation, and protect the skin from environmental damage caused by free radicals

This interaction hampers the proteins from assuming abnormal structures, creating harmful clusters

in another paper published the same year, the tan patch has glucose while the white patch has glycerin, which are definitely not isomers

The upregulation of Sirt3 and Sirt5 may have anti-apoptotic activities (Kincaid and Bossy-Wetzel, 2013), but decreased expression of Sirt1 disrupts the Sirt1-PGC-1 inter-relationships (Lavu et al., 2008)