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o-Tyrosine has been previously considered a biological marker of oxidative stress, but there is accumulating evidence suggesting that it could directly contribute to the toxic effects of oxidative stress in cells and tissues via protein degradation, apoptosis, and proliferation

(3) Combination therapies: combining oxidative cell death inducers with conventional treatments, such as chemotherapy and radiotherapy, can synergistically enhance treatment effectiveness, potentially overcoming drug resistance and improving patient outcomes

In melanoma and lung cancer, antioxidants have been shown to promote metastasis, underscoring the potential efficacy of a pro-oxidant approach in this context

Trujillo, J