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LTRPC2 Ca 2+ -permeable channel activated by changes in redox status confers susceptibility to cell death

However, validated medical treatments (UVB phototherapy, topical corticosteroids, calcineurin inhibitors, JAK inhibitors such as ruxolitinib) can enable partial or complete repigmentation in some patients

2014;40:10031021 Quinn CT, St Pierre TG

All mice were approved by the Laboratory Animal Welfare Ethics committee at Harbin Institute of Technology (Approval No: IACUC- 2024138) and conducted in accordance with the Guide for Care and Use of Laboratory Animals and the institutional ethical guidelines for animal experiments