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Description

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This salt bridge cannot be formed in DRI-A 42 peptides as the (negatively charged) C-terminal of the L-peptide becomes a (positively charged) N-terminus in the DRI-peptide, i.e., there will be a repulsive interaction between the NH3 groups on the N-terminal D-A42 and residue D-K28 (note that we count residues in DRI peptides starting from the C-terminus)