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Budui da glutation regulie oksidativni stres, kada je njegova koncentracija u organizmu nedovoljna moe doi do oteenja koja se povezuju sa razvojem odreenih oboljenja kao to su Parkinsonova bolest, Alchajmer i rak

IAA can also promote tumor growth in some cases (e.g., in renal and esophageal cancer cells), for example, by inducing Ahr in macrophages and Teffs, suppressing antitumor immunity [133]