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10.1053/j.gastro.2010.03.040 Gastroenterology 144 SchliessF.GorgB.FischerR.DesjardinsP.BidmonH

Abstract Background: Chronic liver disease is characterized by progressive hepatic glutathione depletion and oxidative stress, yet antioxidant therapies have historically shown disappointing clinical efficacy in unselected populations

Indeed, a pilot study demonstrated that specific components of Mediterranean diet (i.e., legumes, red meat, and overall proteins) were associated with reduced inflammation and oxidative stress, increased eNOS activity and reduced CVD risk in a cohort of ethnically mixed women (191)

The second, discovered more recently, is based on a distinctly biological pathway, which only occurs within the cells because of the body's metabolism of carbohydrates or sugars