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In The High Costs of Low-Grade Inflammation, Dantzer points out that during chronic inflammation, insulin resistance in the brain decreases glucose and protein metabolism in the astrocytes, forcing the neurons to rely more heavily on the less efficient process of lipid metabolism for energy

Naqvi et al., 2020), highlighting the need for combination strategies and novel delivery platforms (Kulisevsky, 2022

GSH y neurodegeneracin El cerebro es especialmente vulnerable al estrs oxidativo debido a las actividades enzimticas antioxidantes relativamente ms bajas (SOD, GPx, GR y catalasa) comparadas con otros tejidos

The two most important SH2 molecules at this point are the adaptor molecule Grb2 and the enzyme PI3K[251, 252]