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Acknowledgements This work was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) and University of Leicester funded Midlands Integrative Biosciences Training Partnership (MIBTP) [grant number BB/T00746X/1], and was funded in part, by the Wellcome Trust [Grant number 210911/Z/18/Z]

Although these results are still at the preclinical stage, they suggest a therapeutic potential for GHK-Cu that extends well beyond the cosmetic domain

It regulates the polymerization of G-actin to F-actin, which is essential for cell migration and wound healing

In dermal and corneal models, Tb4 accelerates re-epithelialization (Malinda et al., J Invest Dermatol , 1999