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Therefore, although 6-hydroxy-FAD actually acts a dual role as an active cofactor for FSP1 and a potent antioxidant in vitro and may play the same role in the ferroptosis inhibition in human cells at level below our detection limit, we cannot rule out the possibility that 6-hydroxy-FAD may not be stably stored in human cells and the feeding 6-hydroxy-FAD blocks ferroptosis probably by other unclear mechanism

Functional modulation of enterocytes by gram-positive and gram-negative microorganisms

Ryu J, Ku BM, Lee YK, Jeong JY, Kang S, Choi J, et al

10.1016/j.intimp.2024.112563 20 LiangJ.YuY.WangB.LuB.ZhangJ.ZhangH.et al (2013)