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Oxidative stress and hyper-inflammation as major drivers of severe COVID-19 and long COVID: implications for the benefit of high-dose intravenous vitamin C

Moreover, H 2 O 2 , a membrane-permeable mtROS, interacts with intracellular iron to form extremely reactive hydroxyl radicals which damage nuclear DNA [143,144,145]

doi: 10.1038/s41575-018-0061-2 Summary Keywords gut microbiota, oxidative stress, probiotics, colitis, intestinal diseases Citation Sun Y, Wang X, Li L, Zhong C, Zhang Y, Yang X, Li M and Yang C (2024) The role of gut microbiota in intestinal disease: from an oxidative stress perspective