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Setiawan VW, Pandol SJ, Porcel J, Wei PC, Wilkens LR, Le Marchand L,

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Early astrocytic dysfunction is associated with mistuned synapses as well as anxiety and depressive-like behavior in the AppNL-F mouse model of Alzheimers disease

Cytochrome c release assay Cells were fractionated to obtain cytoplasmic and mitochondria-enriched fractions using Dounce homogenization and differential centrifugation as per the Abcam cytochrome c release kit (ab65311)