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Long-Term Safety Evidence While many peptide therapies have been evaluated only in short-term trials, AOD-9604 benefits from long-term safety data extending to 24 weeks of continuous administration

What they found: Dose-dependent stimulation of type II collagen (up to 2.5 baseline at 100 nM) Stimulation of aggrecan (up to 1.8 baseline) Inhibition of MMP-13 by ~40 % Partial protection against IL-1-induced matrix degradation Why it matters: It opened a completely new research area for AOD-9604 beyond lipolysis

Regulatory Status & Prohibited Substances AOD-9604 is not FDA-approved as a drug for any indication