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Furthermore, during normal mitochondrial respiration, approximately 1%2% of electrons leak from the, ETC., reducing oxygen prematurely to form O 2

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For equal amounts of protein, this indicates that DHAR should be more efficient, although the actual in vivo rates will be influenced by several factors, most obviously the relative abundance of the proteins and the in vivo concentrations of the respective oxidants in the compartments where the proteins are located

Hiroshi Kadokura: Disulfide bonds formed between pairs of cysteines are important structural features of many exported proteins