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The Akkermansia species muciniphila has been shown to alter glucose and lipid metabolism as well as intestinal immunity 86 , to strengthen the integrity of the enterocyte monolayer to possibly improve intestinal barrier integrity 87 , and to improve glucose tolerance and reduce visceral adipose tissue inflammation in mice fed an HFD 88

Cytoscape: a software environment for integrated models of biomolecular interaction networks

Shen, J., Yang, X., Dong, A., Petters, R

These neuropathies manifest with symptoms that start in the hands and progressively involve both the lower and upper limbs, indicating potential myelopathy [79, 80]