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3.2 Smoking and oxidative stress in gastric cancer Tobacco smoke from tar and gas phases maintain a variety of compounds, including unstable free radicals and ROS, which can harm organism through oxidative stress

Probably with the progression of the cataract than the consumption of GSH against toxic compounds, the synthesis of GSH is reduced, as the result of deficient availability of substrates and reduced activity of enzymes for its synthesis (-glutamyl-cysteine syntethase)